| abstract |
1. A method of modulating the function and / or expression of a hepatocyte growth factor polynucleotide (HGF) in a patient’s cells or tissues in vivo or in vitro, comprising: contacting said cells or tissues with at least one 5- antisense oligonucleotide 30 nucleotides, wherein said at least one oligonucleotide has a sequence that is at least 50% identical to a sequence that is inversely complementary to a polynucleotide containing 5-30 consecutive nucleotides in the range from 1 to 514 nucleotides The sequence SEQ ID NO: 2, 1 to 936 nucleotides of the sequence SEQ ID NO: 3, or 1 to 1075 nucleotides of the sequence SEQ ID NO: 4; thereby modulating the function and / or expression of said hepatocyte growth factor polynucleotide (HGF) in a patient’s cells or tissues in vivo or in vitro. 2. A method of modulating the function and / or expression of a hepatocyte growth factor polynucleotide (HGF) in cells or tissues of a patient in vivo or in vitro, comprising: contacting said cells or tissues with at least one antisense oligonucleotide consisting of 5-30 nucleotides in length wherein said at least one oligonucleotide has a sequence that is at least 50% identical to the sequence that is inversely complementary to the natural antisense sequence of hepatocyte growth factor polynucleotides (FRG); with modulating, therefore, the function and / or expression of said polynucleotide of hepatocyte growth factor (HGF) in a patient’s cells or tissues in vivo or in vitro. 3. Method for modulating the function and / or expression of hepatocyte growth factor polynucleotide (FRG) � |