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filingDate 2010-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2012111217-A
titleOfInvention MEDICAL DEVICE FOR PLACEMENT IN LIGHT AND METHOD FOR ITS MANUFACTURE
abstract 1. A medical device for placement in the lumen, the body of which is covered with mixed particles consisting of particles of a poorly soluble in water drug substance, the surface of which is modified by a positive charge, and biocompatible nanoparticles. 2. The medical device for placement in the lumen according to claim 1, wherein the surface of the particles of the drug substance is modified with a positive charge by attaching a cationic polymer to their surface. The medical device for placement in the lumen according to claim 2, wherein the cationic polymer is chitosan or a chitosan derivative. A medical device for placement in a lumen according to claim 1 or 2, wherein the particles of the drug substance have an average particle size of 0.1 μm to 5 μm. A medical device for placement in a lumen according to claim 1 or 2, wherein the biocompatible nanoparticles have an average particle size of 300 nm or less. A medical device for placement in a lumen according to claim 1 or 2, wherein, in addition to particles of a drug substance, biocompatible nanoparticles contain the same or another drug substance inside and / or on their surface. The medical device for placement in the lumen according to claim 1 or 2, wherein the biocompatible nanoparticles consist of any of polylactic acid, polyglycolic acid, a lactic and glycolic acid copolymer and a lactate-aspartate copolymer. A medical device for placement in the lumen according to claim 1 or 2, which refers to the type of stent with the dissolution of the drug substance, the body of which is covered with particles of the drug substance and biocompatible nanoparticles. Medical devices
priorityDate 2009-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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