http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012105279-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20 |
| filingDate | 2010-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012105279-A |
| titleOfInvention | METHOD FOR PRODUCING POLYMORPHIC 2- (3-CYANO-4-ISOBUTYLOXYPHENYL) -4-METHYL-5-THIAZOLECARBOXYLIC ACID CRYSTALS WITH ADDITION OF A SOLVENT, BADLY SOLVENT |
| abstract | 1. A method of obtaining crystals of the A-form of 2- (3-cyano-4-isobutyloxyphenyl) -4-methyl-5-thiazolecarboxylic acid, comprising: a step of dissolving by heating 2- (3-cyano-4-isobutyloxyphenyl) -4-methyl -5-thiazolecarboxylic acid in one or many solvents that dissolve the substance well, selected from the group consisting of 1-propanol, 2-propanol, ethanol and acetone; a solution cooling step; and the step of adding to the solution a hydrocarbon solvent poorly dissolving the substance. 2. The production method according to claim 1, in which the solvent, a well-dissolving substance, is one solvent selected from the group consisting of 1-propanol, 2-propanol, ethanol and acetone. The production method according to claim 1 or 2, wherein the solvent, a poorly dissolving substance, is heptane and / or hexane. The production method according to claim 1 or 2, in which the solvent, a poorly dissolving substance, is heptane. |
| priorityDate | 2009-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.