http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012104984-A
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
filingDate | 2012-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2012104984-A |
titleOfInvention | METHOD FOR PHARMACOLOGICAL CORRECTION OF SKELETAL ISCHEMIA ISCHEMIA SILDENAFIL, INCLUDING L-NAME-INDUCED NITROGEN OXIDE DEFICIENCY |
abstract | A method for the pharmacological correction of skeletal muscle ischemia with sildenafil, including with L-NAME-induced nitric oxide deficiency, characterized in that the correction of skeletal muscle ischemia, including with modeling nitric oxide deficiency, by an intraperitoneal administration of a nitric oxide synthesis blocker to a laboratory animal for 7 days N-nitro-L-arginine methyl ester at a dose of 25 mg / kg daily, is carried out by intraperitoneal injection of sildenafil at a dose of 2.2 mg / kg on the first, third and fifth days of the experiment. |
priorityDate | 2012-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.