http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012100715-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1617 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1694 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012100715-A |
| titleOfInvention | DICETOPIPERASINE MICROPARTICLES WITH DEFINED SURFACE SURFACES |
| abstract | 1. Microparticles of diketopiperazine with a specific surface area of less than about 67 m / g. 2. Microparticles of diketopiperazine according to claim 1, in which the specified specific surface area is in the range from about 35 m / g to about 67 m / g. Microparticles of diketopiperazine according to claim 1, wherein said microparticles contain a drug substance or an active agent. Microparticles of diketopiperazine according to claim 3, wherein said specific surface area is less than about 62 m / g. Microparticles of diketopiperazine according to claim 4, wherein said drug substance or active agent is a peptide or protein. Microparticles of diketopiperazine according to claim 5, wherein said peptide is an endocrine hormone. Microparticles of diketopiperazine according to claim 6, wherein said endocrine hormone is insulin, parathyroid hormone, calcitonin, glucagon, glucagon-like peptide-1, oxyntomodulin, an analogue or an active fragment of said endocrine hormone. Microparticles of diketopiperazine according to claim 1, wherein said diketopiperazine is fumaryl diketopiperazine. A dry powder containing microparticles of diketopiperazine according to claim 7.10. A method of forming microparticles of diketopiperazine with a specific surface area ranging from about 35 m / g to about 67 m / g with a 95% confidence limit, comprising: a) dissolving diketopiperazine in an aqueous solution; b) adding an acidic solution to the aqueous solution to obtain a mixture; c) selection of production conditions for the targeted production of microparticles with a specific surface area of approximately 52 m / g; d) precipitation of microparticles of diketopiperazine formed |
| priorityDate | 2009-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 194.