http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011151286-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39591 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 2010-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2011151286-A |
titleOfInvention | LYOPHILIZED RECIPES FOR SMALL MODULAR IMMUNOPHARMACEUTICAL PRODUCTS |
abstract | 1. A formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, where less than 7% of the lyophilized small modular immunopharmaceutical protein exists in aggregated form. The formulation of claim 1, further comprising an excipient selected from the group consisting of sucrose, mannitol, glycine, sodium chloride, dextran, trialose and combinations thereof and / or a buffer selected from the group consisting of histidine, sodium acetate, citrate, phosphate, succinate , Tris and combinations thereof. 3. The formulation according to claim 2, where the mass ratio of non-reducing sugar to a small modular immunopharmaceutical protein is approximately 0.1: 1, 0.2: 1, 0.25: 1, 0.4: 1, 0.5: 1, 1: 1, 2: 1, 2.6: 1, 3: 1, 4: 1 or 5: 1.4. The formulation of claim 2, wherein the formulation further comprises a stabilizer selected from the group consisting of sucrose, sorbitol, mannitol, glycine, trialose, and combinations thereof. The formulation of claim 4, wherein the formulation further comprises an isotonic agent selected from the group consisting of glycine, sorbitol, sucrose, mannitol, sodium chloride, dextrose, arginine, and combinations thereof. The formulation of claim 5, wherein the formulation further comprises a surfactant selected from the group consisting of Polysorbate 20, Polysorbate 80, poloxamers, Triton, and combinations thereof. A formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, sucrose, histidine, methionine and Polysorbate 80.8. The formulation of claim 7, comprising approximately 50 mg / ml small modular immunopharmaceutical protein, approximately 10 mM histidine, approximately 10 mM methionine, approximately 5% sucrose, and approximately 0.01% Polysorbate 80.9. The formulation of claim 7, comprising |
priorityDate | 2009-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.