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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14
filingDate 2010-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2011139287-A
titleOfInvention OXYINDOLIC DERIVATIVES HAVING AGONISTIC ACTIVITY AGAINST MOTHLINE RECEPTOR
abstract 1. The compound of the following formula (I): [Chemical formula 44] where R and R are independently selected from the group consisting of hydrogen, C-Cialkyl and Ci-Ci-cycloalkyl; or, alternatively, R and R, together with the atoms to which they are bonded, form a 3-6 membered ring, which may contain oxygen; said ring is optionally substituted with 1-4 substituents independently selected from the group consisting of halogen, hydroxy, C 1 -C 6 alkyl and C 1-6 alkoxy; R 1 and R 4 independently represent hydrogen or C 1-6 alkyl; R 1 is hydrogen, C 1-6 alkyl or C 1-6 alkoxy C 1-6 alkyl; R 1 and R 2 independently selected from hydrogen, C 1-6 alkyl, C 1-6 hydroxy C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkyl, C 1-6 alkyl C 1 -alkyl, di (1-4C-alkyl) amino 1-4C-alkyl, saturated heterocyclyl and saturated heterocyclyl C 1-6 alkyl; said saturated heterocyclyl and alkyl may independently contain 1-4 C-Calkyl groups; or alternatively, R and R, together with the nitrogen atom to which they are bonded, form a 4-6 membered ring that may contain nitrogen or oxygen, wherein the 4-6 membered ring is optionally substituted with 1-4 substituents independently selected from the group consisting of hydroxy, C 1 -C 6 alkyl, C 1-6 alkoxy, C 1-6 cycloalkyl, amino, 1-4C-alkylamino and di (1-4C-alkyl) amino; A is [Chemical formula 45] where p, q and r are independently 0, 1, 2 or 3; R and R are independently hydrogen, C 1-6 alkyl or C 1-6 cycloalkyl; said alkyl and cycloalkyl are optionally substituted with hydroxy, Ci-Ci-alkyl, amino, Ci-Ci-alkylamino and di (Ci-Ci-alkyl) amino; or R and R may be combined with each other to form a C-C membered ring, which may contain oxygen; or R and R independently can be combined with one or both R and R groups to form alkylene bridges between
priorityDate 2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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