http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011139043-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2010-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011139043-A |
| titleOfInvention | METHOD FOR PRODUCING FUSIDIC ACID CREAM |
| abstract | 1. A method of manufacturing a cream containing fusidic acid, the method comprising the step of using sodium fusidate as the starting active ingredient and converting said sodium fusidate in situ to fusidic acid in a cream base in an oxygen-free environment. The cream manufacturing method according to claim 1, wherein said cream base contains a preservative, an acid, a co-solvent, an emulsifier and a waxy product together with water, preferably purified water. The cream manufacturing method according to claim 1, wherein the step of using sodium fusidate as a starting active ingredient and converting said sodium fusidate in situ to a fusidic acid in a cream base in an oxygen-free environment comprises the following steps: a. heating purified water in an amount of from 20% (by weight) to 75% by weight, preferably from 35% by weight to 50% by weight, more preferably from 40% by weight to 43% by weight in a vessel for the aqueous phase up to a temperature of 70 ° C to 80 ° C, c. adding to the specified vessel for the aqueous phase a preservative selected from the group comprising methylparaben, propylparaben, chlorocresol, potassium sorbate, benzoic acid and the like, either one or any combination thereof in an amount of from 0.05% in a weight ratio to 0.5 % by weight, preferably 0.3% by weight, more preferably 0.2% by weight, more preferably benzoic acid, c. mixing the mixture using a stirrer at a rotation speed of 10 to 50 rpm and maintaining the temperature of the mixture from 70 ° C to 80 ° C, d. adding waxy |
| priorityDate | 2009-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.