abstract |
1. The compound of formula I where Ar is a 5-10 membered aromatic ring containing up to 4 heteroatoms selected from O, S, N (H), SO and SO, where 1-3 ring atoms are optionally and independently substituted with J; R and R are independently: a (C1-C12) aliphatic radical, a (C3-C10) cycloalkyl or cycloalkenyl, [(C3-C10) cycloalkyl or cycloalkenyl] - (C1-C12) aliphatic radical (C6-C10) aryl- (C1-C12) aliphatic radical, (C6-C10) heteroaryl- (C1-C12) aliphatic radical, where up to 3 aliphatic carbon atoms in R and R can be replaced with heteroatoms selected from O , N, S, SO and whether SO, in a chemically stable structure; where each of R and R is independently and optionally substituted with substituents up to 3 selected independently from J; R and R are, independently, hydrogen or a (C1-C12) aliphatic radical, where any a hydrogen atom is optionally replaced with a halogen; where any terminal carbon atom of the R group is optionally substituted with sulfhydryl or hydroxy; or R 4 is phenyl or —CH-phenyl, wherein said phenyl group is optionally substituted with substituents up to 3 independently selected from J; or R and R, together with the atom to which they are attached, are a 3-6 membered ring containing up to 2 heteroatoms selected from N, NH, O, SO and SO; where the ring has up to 2 substituents independently selected from J; R and R are independently: hydrogen, a (C1-C12) aliphatic radical, (C3-C10) cycloalkyl or cycloalkenyl, (C3-C10) - cycloalkyl- (C1-C12) aliphatic radical, (C6-C10) aryl -, (C3-C10) heterocyclyl or (C5-C10) heteroaryl-; where up to two aliphatic carbon atoms in R and R can be replaced by heteroatoms selected from O, N, S, SO and SO; where each of R and R, independently and optionally, is substituted by |