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filingDate 2010-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2011134454-A
titleOfInvention DERIVATIVES FGF21 WITH BINDING ALBUMINE A-B-C-D-E- AND THEIR APPLICATION
abstract 1. A derivative of compound FGF21 having a covalently attached albumin binder of the formula ABCDE-, where A- is an element of formula I, II or III: or where n is 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 or 19, and represents the point of attachment to -B -; - B- is absent, is a bond, or is selected from -B1-, -B2- or a combination thereof, where -B1- is an element of formula IV, V, VI or VII : where is the point of attachment to -B2- or -C-, and # is the point of attachment to A- or -B2-; and -B2- is an element of formula IIX, IX or XXVIII or a combination of up to four elements of formula IIX and / or formula IX and / or formula XXVIII: where b is 0, 1 or 2, c is 0, 1 or 2, when provided that b is 1 or 2 when c is 0, and b is 0 when c is 1 or 2, is the point of attachment to -C-, -B1- or to another -B2-, and # is the point joining to A-, -B1- or to another -B2- or where d is 1 or 2, e is 0, 1 or 2, is the point of attachment to -C- or -B1-, and # is the point of attachment to A- or -B1-, or where and 2, 3 il 4, represents the point of attachment to —C— or —B1—, and # represents the point of attachment to A — or —B1 -; —C— is absent, represents a bond, or is an element of formula X or XI: where p is 0 , 1, 2, 3, 4, 5, or 6, q is 0, 1, 2, 3, 4, 5, or 6, is the point of attachment to -D-, -E- or the FGF21 compound, and # is the point joining to -B-; or where k is 0, 1, 2, 3, 4, 5, 11 or 23, m is 0, 1, 2, 3, 4, 5 or 6, * represents the point of attachment to -D-, -E- or the compound FGF21; and # represents the point of attachment to -B -; - D- is absent, represents a bond or is an element of the formulas
priorityDate 2009-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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