http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011134316-A
Outgoing Links
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|---|---|
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| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243 |
| filingDate | 2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011134316-A |
| titleOfInvention | PLANE NANO-COMPOUNDS AND WAYS OF THEIR APPLICATION |
| abstract | 1. A biocompatible conjugated polymer nanoparticle, comprising: a copolymer backbone, a plurality of side chains covalently linked to said backbone; a plurality of platinum compounds dissociatively linked to said side chains. 2. A nanoparticle according to claim 1, characterized in that the plurality of platinum compounds is selected from Pt (II) compounds, Pt (IV) compounds and any combination thereof. A nanoparticle according to claim 1, characterized in that said copolymer contains maleic acid monomers. A nanoparticle according to claim 1, characterized in that said side chains are selected from the group consisting of polymers, monosaccharides, dicarboxylic acids, polyethylene glycol (PEG), and combinations thereof. A nanoparticle according to claim 1, characterized in that said platinum compound is a Pt (II) compound selected from the group consisting of cisplatin, oxaliplatin, carboplatin, paraplatin, sartraplatin, and combinations thereof. The biocompatible conjugated polymer nanoparticle according to claim 1, wherein the copolymer is poly (isobutylene-alt-maleic acid) containing from 25 to 50 monomer units; a plurality of PEG side chains covalently bonded to the main chain having a molecular weight of from 1000 to 3000 Daltons, and the number of said PEG side chains is from 50% to 100% of the number of monomer units of said polymer main chain; and the number of side groups of cisplatin is from 25% to 75% of the number of monomer units of the polymer backbone. 7. The biocompatible conjugated polymer nanoparticle according to claim 1, wherein the copolymer is a poly (isobutylene-alt-maleic acid) containing |
| priorityDate | 2009-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465838247 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID164031976 |
Total number of triples: 36.