http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011131293-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-974 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 |
| filingDate | 2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011131293-A |
| titleOfInvention | METHOD FOR DETERMINING SPACE-TEMPORAL DISTRIBUTION OF PROTEOLYTIC ENZYME ACTIVITY DISTRIBUTION IN A HETEROGENEOUS SYSTEM, DEVICE FOR IMPLEMENTATION OF THE SPECIFIED METHOD AND DIAGNOSTIC OF DISTURBANCES OF THE HEMOPHYRENOSISTEMOSTEMOSISTEMOSIS |
| abstract | 1. A method for determining the spatiotemporal distribution of the activity of a proteolytic enzyme in a heterogeneous system, which consists in providing an in-vitro system that contains a sample of the test medium, consisting of one of blood plasma, whole blood, water, lymph, colloidal solution, crystalloid solution both the gel and the proteolytic enzyme or its precursor, which is distributed in a sample of the test medium, are immersed in an in-vitro system fluorogenic substrate, in the interaction of the proteolytic enzyme with flu The substrate is cleaved with the fluorophore separated from it, the sample of the test medium is irradiated at specified times with exciting radiation to excite the fluorophore, which is formed as a result of the splitting of the fluorogenic substrate with a proteolytic enzyme, and at the specified times, the camera records the fluorophore in vitro, thereby determining the spatial distribution of the fluorophore, illuminate about a sample of the test medium and the optical characteristics of the test sample are recorded by the camera, i.e. light scattering and light transmission at predetermined points of the in vitro system, from the distribution of the fluorophore fluorescence intensity, the spatiotemporal distribution of the proteolytic enzyme activity is obtained by solving the inverse problem of the “diffusion-convection reaction” type taking into account the degree of binding of the fluorophore in the medium to the components of the medium, and the degree of fluorophore binding obtained from the optical characteristics of |
| priorityDate | 2011-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.