http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011127680-A

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filingDate 2009-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2011127680-A
titleOfInvention Drugs in the form of an enema and their use
abstract 1. An enema preparation containing a photosensitizer comprising 5-aminolevulinic acid (5-ALA) or a precursor or derivative thereof, and at least one pharmaceutically acceptable carrier or excipient and further comprising one or more of the following: a) one or more viscosity increasing agents; b) one or more mucoadhesive agents or one or more mucolytic agents; c) one or more penetration enhancers; ig) one or more chelating agents. 2. An enema preparation according to claim 1, wherein said photosensitizer is a 5-ALA derivative or a pharmaceutically acceptable salt thereof, preferably 5-ALA ester or a pharmaceutically acceptable salt thereof. The enema preparation according to claim 1, wherein said photosensitizer is a compound of formula I or a pharmaceutically acceptable salt thereof: wherein R 1 represents a substituted or unsubstituted alkyl group, and each R independently represents a hydrogen atom or an R group. An enema preparation according to claim 3, wherein each R represents hydrogen and R represents an unsubstituted alkyl group, preferably a C-C1-6 alkyl group. An enema preparation according to claim 1, comprising: (a) one or more viscosity increasing agents; or (b) one or more mucoadhesive agents or one or more mucolytic agents; or (c) one or more than one penetration enhancer; or (d) one or more chelating agents. 6. An enema preparation according to claim 1, containing (b) one or more mucolytic agents, preferably in combination with (c) one
priorityDate 2008-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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