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filingDate 2009-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2011127120-A
titleOfInvention NEW 4- (HETEROCYCLOalkyl) BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, METHOD FOR PRODUCING THEM AND USE THEREOUS IN TREATMENT OF HUMAN, AND ALSO IN COSMETICS
abstract 1. The compounds of general formula (I) below: in which: R1, R2, R3 and R4, which may be the same or different, are: - hydrogen, - CC-alkyl radical, - hydroxymethyl, hydroxyethyl, - (CC -alkoxy) carbonyl, - CC-alkoxy, - hydroxyl, or R1 and R2 are bonded to each other and to the carbon atom to which they are attached to form a carbon cycle containing 5 or 6 carbon atoms, and R3 and R4, which can be the same or different, are: - hydrogen, - a CC-alkyl radical, or R1 and R4 are linked together to form a chain - (CH ) or - (CH) -, and R2 and R3, which may be the same or different, are: - hydrogen, - CC-alkyl radical, X represents an oxygen atom or a sulfur atom, Y represents hydrogen, a chlorine atom or a fluorine atom, the value of m can be 1 or 2, and the value of n can be 0 or 1, and when n = 0, then m = 1 or 2, and when n = 1, then m = 1, as well as salts of the compounds general formula (I) and their isomeric and enantiomeric forms. 2. A compound according to claim 1, characterized in that it is in the form of a salt formed with a base selected from organic bases and inorganic bases. The compound according to claim 1, characterized in that it is in the form of a hydrate or solvate. The compound according to claim 2, characterized in that it is in the form of a hydrate or solvate. A compound according to any one of claims 1 to 4, characterized in that: R1 is hydrogen, a CC-alkyl radical or hydroxymethyl radical, R2 is hydrogen, R3 is hydrogen, R4 is hydrogen, X is is an oxygen atom, - Y represents a hydrogen or fluorine atom, - m = 1 and n = 1, as well as salts of these
priorityDate 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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