http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011126215-A
Outgoing Links
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-02 |
filingDate | 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2011126215-A |
titleOfInvention | NEW SUBSTITUTED OCTAHYDROCYCLOPENT [c] PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKS |
abstract | 1. The compound of formula (I), or a pharmaceutically acceptable salt, prodrug, prodrug salt thereof, or a combination thereof, in which L is C (O), S (O), SON (R), C (O) O or - (CRR) -; R is alkyl, G, -CH (G), - (CRR) -G, - (CRR) -CH (G), - (CRR) -N (R), - (CRR) -N (R) - C (O) O (alkyl), - (CRR) -N (R) -C (O) (alkyl) or - (CRR) -N (R) -SOR; or L-R together means hydrogen, alkyl, hydroxyalkyl, G or -CH (G); L means - (CRR) -, C (O), C (O) N (R), S (O), SON (R) or C ( O) O; R is alkyl, G, -C (R) (G) (G), - (CRR) -G, - (CRR) -CH (G) (G), - (CRR) -N (R) -C (O) O (alkyl), - (CRR) -N (R) -C (O) OG, - (CRR) -N (R) -C (O) (alkyl), - (CRR) -N (R) -SOR, - (CRR) -N (R) (R), - (CRR) -N (R) -C (O) N (R) - (alkyl), or - (CRR) -N ( R) -C (O) N (R) -G; or L-R together represent alkyl, G or -C (R) (G) (G); m and p, in each case, each independently, 1, 2, 3, 4, 5 or 6; n and q in each case, each independently 1, 2, 3, 4 or 5; R, R, R and R, in each case, each independently hydrogen, alkyl, arylalkyl, halogen, haloalkyl or OR; or R and R, or R and R, together with the carbon atom to which they are attached, can form a cycloalkyl ring; R, R, R and R, in each case, are each independently hydrogen, alkyl, halogen, haloalkyl, OR, cycloalkylalkyl, heteroaryl, arylalkyl, or heteroarylalkyl; moreover, aryl, cycloalkyl and heteroaryl aryl groups, cycloalkyl and heteroaryl are each independently unsubstituted or substituted with 1, 2, 3, 4 or 5 substituents independently selected from the group consisting of alkyl and haloalkyl; G, G and G, in each case are each independently aryl, cycloalkyl, cycloalkenyl, heteroaryl or heterocycle; moreover, G, G and G in each case are each independently unsubstituted or substituted with 1, 2, 3, 4 or 5 substituents selected from the group consisting of alkyl, alkenyl, alkynyl, cyano, haloalkyl, halogen, nitro, oxo, phenyl, N (R), N (R) C (O) R, OR, C (O) R, C (O) OR, C ( |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-022741-B1 |
priorityDate | 2008-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.