http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011125925-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011125925-A |
| titleOfInvention | METHOD FOR PRODUCING TOXIN Actinobacillus pleuropneumoniae ApxI USING A CULTURAL MEDIA CONTAINING A CALCIUM-BOROGLUCONATE COMPLEX |
| abstract | 1. A method of obtaining RTX-toxin ApxI by culturing bacteria Actinobacillus pleuropneumoniae in a culture medium that provides the growth of bacteria, and to this medium is added a calcium salt to form calcium ions in the medium, characterized in that the culture medium contains borogluconate for the formation of a calcium complex in the medium -borogluconate. 2. The method according to claim 1, characterized in that the concentration of borogluconate is less than 60 mmol / l. The method according to claim 2, characterized in that the concentration is in the range from 25 to 45 mmol / L, preferably 40 mmol / L. A method according to any of the preceding claims, characterized in that the calcium salt is calcium borogluconate. The method according to claim 1, characterized in that during the cultivation, air is passed through the liquid medium, and the air contains carbon dioxide above the atmospheric level. The method according to claim 5, characterized in that the air contains 5 vol.% Carbon dioxide. |
| priorityDate | 2008-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.