http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011125601-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 |
| filingDate | 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011125601-A |
| titleOfInvention | PHARMACEUTICAL COMPOSITIONS OF CLOSTRID TOXIN |
| abstract | 1. He is an animal protein-containing pharmaceutical composition of clostridial toxin in solid form, containing clostridial toxin as an active ingredient, an effective amount of a sugar excipient and an effective amount of a surface-active excipient. The composition of claim 1, wherein the excipient sugar is a monosaccharide, disaccharide or trisaccharide. The composition of claim 1, wherein the monosaccharide is sucrose or trehalose. The composition of claim 1, wherein the surfactant excipient is poloxamer, polysorbate, polyoxyethylene glycol dodecyl ether or polyoxyethylene octyl phenyl ether. The composition of claim 1, wherein the clostridial toxin as an active ingredient is stable for at least one year when stored at ambient temperature or below freezing. The composition of claim 1, wherein the composition is buffered to a pH of from about 5.5 to about 6.5.7. The composition of claim 6, wherein the composition is buffered using citrate buffer, phosphate buffer, histidine buffer or histidine phosphate buffer. The composition of claim 1, wherein the composition further comprises an effective amount of sodium chloride. The composition of claim 1, wherein the composition further comprises an effective amount of a non-protein polymeric excipient. The composition of claim 9, wherein the non-protein polymeric excipient is dextran, polyethylene glycol, polyethyleneimine, polyvinylpyrrolidone, polyvinyl acetate, inulin, starch or a starch derivative. |
| priorityDate | 2008-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.