http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011124039-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2010-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011124039-A |
| titleOfInvention | METHOD FOR IDENTIFICATION OF IMMUNE BINDING SUBSTANCES OF CELL SURFACE ANTIGENS |
| abstract | 1. A method for identifying an immune binder that specifically binds to a target antigen on a cell surface, which comprises: (a) the presence of a plurality of expressing immune binders cells functionally linked to a first sortable label; (b) the presence of a plurality of antigen-expressing cells, functionally associated with a second sortable label, where the target antigen is on the surface of the antigen expressing cell; (c) the interaction of antigen expressing cells with cells, express crosslinking immune binders; and (d) separating from a plurality of cells expressing immune binders, one or more cells expressing immune binders that can specifically bind to antigen-expressing cells using a cell sorter, where the presence of the first and second sortable labels in one cell complex is an indicator of the binding of the cell expressing the immune binder to the antigen-expressing cell, thereby identifying the immune binder that binds to the miche evym antigenom.2. The method of claim 1, further comprising the clonal isolation of cells expressing the immune binders obtained in step (d), followed, in some cases, by the clonal expansion of the cloned cells. The method of claim 2, further comprising obtaining a nucleic acid sequence encoding an immune binder from isolated cells expressing the immune binder. The method according to claim 3, where the nucleic acid sequence |
| priorityDate | 2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.