http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011121681-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4846 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 |
| filingDate | 2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011121681-A |
| titleOfInvention | MEDICAL PRODUCTS FOR TREATMENT OF BLOOD COAGING DISORDERS |
| abstract | 1. A drug containing a factor XIa concentrate without thrombin or a coagulation factor concentrate containing a factor XIa without thrombin to obtain a drug that does not form thrombin during storage and to obtain a parenterally applicable drug that does not form thrombin during or after lyophilization, storage and reconstitution. 2. The drug according to claim 1, which contains serpins and / or high molecular weight kininogen or its cleavage products. The drug according to claim 1, which is nanofiltered to improve safety against viruses, either before or after preparation, preferably by means of nanofilters with a pore diameter of ≤20 nm or it was filtered by means of an ultrafilter of 1000 kDa. The medicament according to claim 1, which is made safe against viruses by treatment with a solvent / detergent and subsequent removal of the solvent and detergent. The drug according to claim 1, which is filled under sterile and pyrogen-free conditions and lyophilized and inactivated against viruses by heating the filled, lyophilized drugs at not less than 90 ° C and not more than 140 ° C for 30-180 min. . Factor XIa concentrate without thrombin or coagulation factor concentrate containing factor XIa without thrombin according to claim 1, characterized in that it is obtained by fractionation of plasma or serum or by genetic engineering. Factor XIa concentrate without thrombin or coagulation factor concentrate containing factor XIa without thrombin according to claims 1 and 6, characterized in that it is safe against viruses and pyrogen-free. Medicinal Wed |
| priorityDate | 2009-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.