http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011117584-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2009-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011117584-A |
| titleOfInvention | GENETIC TEST FOR THE ACCUMULATION OF COPPER IN THE LIVER OF DOGS |
| abstract | 1. A method for determining a dog’s predisposition to accumulate copper in the liver, comprising determining the presence or absence in the dog’s genome of (a) polymorphism in the GOLGA5, ATP7a or UBL5 gene, which indicates a predisposition to copper accumulation in the liver, and / or (b) polymorphism, in non-equilibrium coupling with the indicated polymorphism (a). ! 2. The method according to claim 1, comprising determining the presence or absence of at least one polymorphism (a) and at least one polymorphism (b). ! 3. The method according to claim 1, where the polymorphism is a single nucleotide polymorphism (SNP). ! 4. The method according to claim 3, including determining the presence or absence of one or more SNPs selected from BICF2P506595 (SEQ ID NO: 1), BICF2P772765 (SEQ ID NO: 2), BICF2S2333187 (SEQ ID NO: 3), BICF2P1324008 (SEQ ID NO: 4), BICF2P591872 (SEQ ID NO: 5), ATP7a_Reg4_F_9 (SEQ ID NO: 131), UBL5_Reg1F_16 (SEQ ID NO: 132), golga5_Reg1_24 (SEQ ID NO: 133), golga5_26 (SEQ ID NO: 134) , golga5_27 (SEQ ID NO: 135), golga5_28 (SEQ ID NO: 136), golga5_29 (SEQ ID NO: 137), golga5_30 (SEQ ID NO: 138), golga5_31 (SEQ ID NO: 139), atp7areg17_32 (SEQ ID NO: 140), atp7areg17_33 (SEQ ID NO: 141) and one or more SNPs that are in non-equilibrium coupling with them. ! 5. The method according to claim 4, including determining the presence or absence of SNPs BICF2P506595 (SEQ ID NO: 1), BICF2P772765 (SEQ ID NO: 2), BICF2S2333187 (SEQ ID NO: 3), BICF2P1324008 (SEQ ID NO: 4) and BICF2P591872 (SEQ ID NO: 5). ! 6. The method according to claim 1, where the dog inherits the genetic characteristics of the breed Labrador Retriever. ! 7. A database containing information on one or more polymorphisms in the GOLGA5, ATP7a or UBL5 genes, and / or on one or more polymorphisms that are in disequilibrium coupling with them, and their relationship to the dog’s predisposition to accumulate copper in the liver. ! 8. A method for determining a dog's predisposition to the accumulation of copper in the liver, including:! (a) input to a computer data system |
| priorityDate | 2008-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 14.