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filingDate 2009-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2012-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2011111744-A
titleOfInvention OIL-SYNTHESIS MICRO-ORGANISMS ENRICHED WITH ORGANIC SELENIUM ON THE BASIS OF COMPOUNDS OF HYDROXYLIC ACIDS OF SELENIUM, AND THEIR APPLICATION IN FOOD, COSMETICS AND PHARMACY
abstract 1. A method of enriching non-photosynthetic microorganisms with organic selenium, characterized in that the said non-photosynthetic microorganisms are cultured in a medium containing a compound such as selenium hydroxy acid. ! 2. The method according to claim 1, wherein the compound such as selenium hydroxy acid is a compound of general formula (I), which is described below, by a salt, a stereoisomer, a mixture of stereoisomers in any proportions, such as a racemic mixture, or an ester or amide derivative of this compound,! ! where n = 0, 1 or 2; ! R1 = OH, OCOR3, OPO3H2, OPO3R4R5 or OR6; ! R2 = OH, R3, NHR7, S-cysteinyl or S-glutathionyl; ! provided that if n = 1 and R2 = OH, then R1 cannot be OH; ! R3 = alkoxyl, ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a and 6b, S-cysteinyl, S-glutathionyl or a group selected from the following groups:! ,! ,,,! ,! ,! ! or , ! OR4 = alkoxyl (C1-C26), ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a et 6b, or a group selected from the following groups:! ,! ,,,! ,! ,! ! or , ! OR5 = alkoxyl (C1-C26), ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a et 6b or a group selected from the following groups:! ,! ,,,! ,! ,! ! or , ! OR6 = pyruvate, lactate, citrate, fumarate, maleate, myristate, palmitate, stearate, palmitoleate, oleate, linoleate, a residue of a natural fatty acid or 13-cis retinoate; ! NHR7 = NH2, NH-alkyl (C1-C26), a residue of a natural amino acid or a residue of a natural amine. ! 3. The method according to claim 1 or 2, in which said compound of the type selenium hydroxy acid corresponds to the following formula (Ia):! ! or its salt, stereoisomer or mixture of stereoisomers in any proportions, such as a racemic mixture, ether or amide,
priorityDate 2008-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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