http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011105058-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-28 |
| filingDate | 2009-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011105058-A |
| titleOfInvention | DERIVATIVES OF CETRAGHYDROCINNOLINE |
| abstract | 1. The compounds of formula (I):! ! A is CR-Rb or -CH2-CH2-; ! R1 represents hydrogen or alkyl; ! R2 is hydrogen or alkyl; ! R3 is alkyl, cycloalkyl, cycloalkylalkyl, aryl, substituted aryl, 1H-pyrazolyl or substituted 1H-pyrazolyl, where substituted aryl is aryl substituted by 1-3 substituents independently selected from alkyl, halogen and haloalkyl, and where substituted by 1H- pyrazolyl is 1H-pyrazolyl substituted with 1-3 substituents independently selected from alkyl and aryl; ! Ra is hydrogen or methyl; ! Rb represents hydrogen or methyl; or ! Ra and Rb together with the carbon atom to which they are attached form cyclopropyl, cyclobutyl or cyclopentyl; ! with the proviso that when Ra and Rb are both hydrogen or both are methyl at the same time, then R3 is (1-methylcyclopropyl) methyl; ! and their pharmaceutically acceptable salts and esters. ! 2. The compounds of claim 1, wherein A is CRaRb, and wherein Ra and Rb together with the carbon atom to which they are attached form cyclopropyl. ! 3. The compound according to claim 1 or 2, where A represents —CH 2 —CH 2 -. ! 4. The compounds according to claim 1 or 2, where R1 represents hydrogen or methyl. ! 5. The compound according to claim 1 or 2, where R2 is hydrogen or methyl. ! 6. The compounds according to claim 1 or 2, where R3 is alkyl, cycloalkyl, cycloalkylalkyl, phenyl, substituted phenyl, 1H-pyrazolyl or substituted 1H-pyrazolyl, where substituted phenyl is phenyl substituted by 1-3 substituents independently selected from alkyl, halogen and halogenated, and where substituted 1H-pyrazolyl is 1H-pyrazolyl, substituted� |
| priorityDate | 2008-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.