http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011101593-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-04 |
| filingDate | 2009-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011101593-A |
| titleOfInvention | METHODS FOR PRODUCING BICYCLIC COMPOUNDS BASED ON IMIDAZOLE |
| abstract | 1. The method of obtaining the compounds of formula I:! ! comprising the interaction of the compounds of formula II:! ! with the compound of formula III:! ! under conditions sufficient to form a compound of formula I, where:! A represents an optionally substituted heterocycle; ! R1 is N (R1A) 2, hydrogen, hydroxyl or optionally substituted alkyl, aryl, alkylaryl, arylalkyl, heteroalkyl, heterocycle, alkyl heterocycle or heterocycloalkyl; and! each R1A is independently hydrogen or optionally substituted alkyl, aryl, alkylaryl, arylalkyl, heteroalkyl, heterocycle, alkyl heterocycle or heterocycloalkyl. ! 2. The method according to claim 1, in which A is an optionally substituted dihydroimidazole, dihydroisoxazole, dihydropyrazole, dihydrothiazole, dioxolane, dithiolan, dithiol, imidazole, isoxazole, isoxazolidine, oxathiolane or pyrazole. ! 3. The method according to claim 1, in which conditions sufficient to form a compound of formula I include a solvent and a base. ! 4. The method according to claim 3, wherein the solvent is an alcohol (eg, methanol, ethanol, isopropanol), an ether (eg, tetrahydrofuran, methyl tert-butyl ether, methyltetrahydrofuran, dimethoxyethane) or a mixture thereof. ! 5. The method according to claim 3, in which the base is a metal alcoholate (for example, sodium methylate, sodium ethylate, potassium tert-butylate). ! 6. A method of obtaining a compound of formula I (a):! ! comprising the interaction of the compounds of formula II (a):! ! with 1-amino-3,4,5,6-tetrahydroxyhexan-2-one:! ! under conditions sufficient to form a compound of formula I (a), where:! X represents CR2, CHR2, N, NR3, O or S; ! Y represents CR2, CHR2, N, N |
| priorityDate | 2008-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.