http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2011101477-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
| filingDate | 2009-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2011101477-A |
| titleOfInvention | Means and method of transdermal delivery of estrogen |
| abstract | 1. A transdermal drug delivery system comprising a layer containing a drug and determining an active surface area and comprising a polymer matrix containing estradiol, said system containing more than 0.156 mg / cm2 of estradiol and providing an estradiol flux greater than 0.01 mg / cm2 / day, based on the area of the active surface. ! 2. The transdermal drug delivery system according to claim 1, characterized in that said polymer matrix comprises a polymer mixture comprising an acrylic adhesive, silicone adhesive and soluble polyvinylpyrrolidone (PVP). ! 3. The transdermal drug delivery system according to claim 1, characterized in that said polymer matrix comprises about 2-25% by weight of acrylic adhesive, about 45-70% by weight of silicone adhesive, about 2-25% by weight of soluble PVP, about 5-15% of a penetration enhancer and about 0.1-10% by weight of estradiol, all of which are based on the total dry weight of said polymer matrix. ! 4. The transdermal drug delivery system according to claim 3, characterized in that said penetration promoting substance comprises oleyl alcohol. ! 5. Transdermal drug delivery system according to claim 3, characterized in that the penetration promoting substance comprises dipropylene glycol. ! 6. The transdermal drug delivery system according to claim 3, characterized in that said penetration promoting substance comprises oleyl alcohol and dipropylene glycol. ! 7. Transdermal drug delivery system |
| priorityDate | 2008-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.