http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010142353-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N33-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N59-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate | 2009-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2010142353-A |
titleOfInvention | WATER PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOLIC COMPLEXES |
abstract | 1. A multi-dose ophthalmic composition comprising:! a first polyol, wherein the first polyol is selected from mannitol, sorbitol, or a combination thereof, where the first polyol is at least 0.01, but less than about 0.5% w / v of the composition; ! a second polyol, wherein the second polyol is selected from propylene glycol, glycerol, or a combination thereof, wherein the second polyol is at least 0.1, but less than about 5% w / v of the composition; ! borate, where the borate is at least 0.05% w / v of the composition, but less than 0.5% w / v of the composition; ! an antimicrobial preservative, wherein the preservative is at least 0.0003, but less than about 0.003% w / v of the composition, and where the preservative is a polymeric quaternary ammonium compound,! therapeutic component; and! water. ! 2. The composition according to claim 1, where the composition corresponds to Ph. Eur. A, Ph. Eur. B or both. ! 3. The composition according to claim 1, where the preservative comprises polyquaterium-1. ! 4. The composition according to claim 1, where the composition essentially does not contain any chlorine-containing components. ! 5. The composition according to claim 1, where the composition essentially does not contain benzalkonium chloride. ! 6. The composition according to claim 1, further comprising a surfactant. ! 7. The composition of claim 6, wherein the surfactant is HCO-40. ! 8. The composition of claim 7, wherein the HCO-40 is at least about 0.03, but less than about 0.5% w / v of the composition. ! 9. The composition according to claim 1, where the resistance of the composition to normalizing the pH of the tear after instillation in the eye is less than 15 μl per 1M NaOH / ml of the composition. ! 10. The composition according to claim 1, where the resistance of the composition to normalize the pH of the tear after instillation in the eye with |
priorityDate | 2008-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.