http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010141940-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4166 |
| filingDate | 2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010141940-A |
| titleOfInvention | SELECTIVE ALPHA2-ADRENERGIC AGENTS AND WAYS OF THEIR APPLICATION |
| abstract | 1. A method of treating pain, comprising administering to the mammal, if necessary, a pharmaceutical composition comprising a therapeutically effective dose of at least one compound having the structure:! ! where X is O, S, or NH; ! n and m are independently from each other from 1 to 5; ! each R1 and R2, independently of one another, is H, alkyl, cycloalkyl, aryl, alkenyl, alkynyl, halide, hydroxy, alkoxy, trifluoromethyl, —N (R6) 2, —CN, CO2R6, or —CH2OH; and! each R3, R4, R5 and R6, independently of one another, is H or lower alkyl; or a combination thereof, or their pharmaceutically acceptable salts, hydrates, solvates, crystalline forms, isomers, tautomers, enantiomers and diastereomers. ! 2. The method according to claim 1, where each R1 and R2 independently of one another is H, lower alkyl, fluoro, chloro, bromo, trifluoromethyl, hydroxy or methoxy. ! 3. The method according to claim 1, where X is S.! 4. The method according to claim 3, where each R1 and R2 independently of each other represents H, lower alkyl, fluoro, chloro, bromo, trifluoromethyl, hydroxy or methoxy. ! 5. The method according to claim 4, where the compound has the structure:! ! ! 6. The method according to claim 1, where X represents NH. ! 7. The method according to claim 6, where each R1 and R2 independently of each other represents H, lower alkyl, fluoro, chloro, bromo, trifluoromethyl, hydroxy or methoxy. ! 8. The method according to claim 7, where the connection has a structure! ! ! ! ! ! ! ! ! 9. The method according to claim 1, where X represents O.! 10. The method according to claim 9, where each R1 and R2 independently of one another is H, lower alkyl, fluoro, chloro, bromo, trifluoromethyl, hydroxy or methoxy. ! 11. The method according to claim 9, where the connection has a structure! ! ! ! 12. The method according to claim 1, where the pharmaceutical � |
| priorityDate | 2008-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.