http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010140598-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10 |
| filingDate | 2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010140598-A |
| titleOfInvention | SPIRINE DERIVATIVES PARTENIN AS NEW ANTI-CANCER AGENTS |
| abstract | 1. Spiro derivatives of partinin with the general structural formula 1:! ! where the X values are selected from the group consisting of nitrile oxide, nitron and azide. ! 2. The derivatives of claim 1, wherein said spiro derivative is spiroisoxazoline having the general structural formula 1a: !! where R is selected from the group consisting of hydrogen, alkyl substituents, namely methyl, ethyl, propyl and their higher homologues, linear or branched, including alicyclic, such as cyclopentane, cyclohexane or rings with a higher content of members, condensed rings, alkyl groups substituted with aryl / heteroaryl, including the benzyl group or its higher homologues, which may include unsaturated alkyl groups, such as cinnamyl, crotyl, prenyl substituents; and R may also be an aryl substituent in the first position of the isoxazoline ring of structure 1a, namely, substituted phenyl, with the exception of 3,4-methylenedioxyphenyl, naphthyl, anthracenyl, phenanthrenyl or other heteroaromatic ring systems such as pyridinyl, indolyl, benzofuryl, furyl , theophenyl, oxazolyl, isoxazolyl or any other single or fused ring heteroaromatic system. ! 3. The derivative of claim 1, wherein said spiro derivative is a spiroisoxazolidine derivative having the general structural formula 1b:! ! where the R / R 'value is selected from the group consisting of hydrogen, alkyl substituents, namely methyl, ethyl, propyl and their higher homologues, linear or branched, including alicyclic, such as cyclopentane, cyclohexane or rings containing higher |
| priorityDate | 2008-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.