http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010138647-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
| filingDate | 2009-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010138647-A |
| titleOfInvention | COMBINED THERAPY 238 |
| abstract | 1. A combination product that contains a VEGFR tyrosine kinase inhibitor or a pharmaceutically acceptable salt thereof and an mTOR selective kinase inhibitor or a pharmaceutically acceptable salt thereof, in combination with a pharmaceutically acceptable adjuvant, diluent or carrier. ! 2. The combined product according to claim 1, containing 4- (4-fluoro-2-methyl-1H-indol-5-yloxy) -6-methoxy-7- (3- (pyrrolidin-1-yl) propoxy) quinazoline or a pharmaceutically acceptable salt thereof, and an mTOR selective kinase inhibitor, or a pharmaceutically acceptable salt thereof, in combination with a pharmaceutically acceptable adjuvant, diluent or carrier! where the mTOR selective kinase inhibitor is selected from any of the compounds! 5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -2-methoxy-N-methylbenzamide; ! 4- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] aniline; ! 6- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -1H-indazol-3-amine; ! 8- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -1,2,3,4-tetrahydro-1,4-benzodiazepin-5- he; ! 5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -2-methoxy-N-methylbenzamide; ! 5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] pyridin-2-amine; ! N- [3- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] phenyl] methanesulfonamide; ! 3- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] aniline; ! 5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [6,5-d] pyrimidin-7-yl] -2-ethoxybenzamide; ! 5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -2- (difluoromethoxy) -N-methylbenzamide; ! 5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -1H-indazol-3-amine; ! [5- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] -2-methoxyphenyl] methanol; ! N - [[4- [2,4-bis [3-methylmorpholin-4-yl] pyrido [5,6-e] pyrimidin-7-yl] phenyl] |
| priorityDate | 2008-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.