abstract |
1. The compound corresponding to formula (I):! ! wherein: ! - X is a divalent (C1-C5) alkylene radical unsubstituted or substituted one or more times on the carbon atom by a fluorine atom or (C1-C3) alkyl; ! - R1 means:! the group -NR8R9; ! piperidin-4-yl radical or piperidin-3-yl radical unsubstituted or substituted one or more times by (C1-C4) alkyl, (C3-C5) cycloalkyl, moreover, carbon atoms may also be substituted by one or more fluorine atoms; ! - R2 means a halogen atom, an Alk group, an OAlk group; ! R3 is methoxy; ! - R4 means a hydrogen atom, a halogen atom, an Alk group, hydroxy, an OAlk group; ! - R5 represents a hydrogen atom, a halogen atom, an Alk group, a hydroxy group, an OAlk group, a —CO2Alk group, a —CH2OH radical; ! - R6 is a hydrogen atom, an Alk group, hydroxy, an OAlk group, (C3-C5) cycloalkyloxy, a group —NR10CONR11R12; ! - R7 means a hydrogen atom, a halogen atom, an Alk group, hydroxy, an OAlk group; ! - or R7 is in position 3 of phenyl, and together with R8 they mean a trimethylene radical; ! - R8 and R9 each independently mean a hydrogen atom or (C1-C4) alkyl; ! or R8 and R9 together with the nitrogen atom to which they are attached form a saturated or unsaturated heterocyclic radical with 3-10 units, said heterocyclic radical being unsubstituted or substituted one or more times by amino, dimethylamino, hydroxy, Alk group, (C3 —C5) cycloalkyl, an OAlk group, a —SO2 — Alk radical, wherein the carbon atoms may also be substituted with one or more fluorine atoms; ! - R10 represents a hydrogen atom or (C1-C4) alkyl; ! - R11 and R12 each independently mean a hydrogen atom or (C1-C4) alkyl; ! - Alk means (C1-C4) alkyl unsubstituted or substituted once or more by a fluorine atom; ! in forms |