http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010136326-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 |
filingDate | 2010-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2010136326-A |
titleOfInvention | COMBINATIONS FOR THE TREATMENT OF DISEASES, INCLUDING CELL PROLIFERATION |
abstract | 1. A pharmaceutical composition comprising effective amounts:! (i) compounds of formula (I)! ! in which R1, R2, which may be the same or different, are hydrogen or optionally substituted C1-C6 alkyl, or! R1 and R2 together represent a 2- to 5-membered alkyl bridge, which may contain 1-2 heteroatoms,! R3 is hydrogen or a group selected from the group consisting of optionally substituted C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl and C6-C14 aryl, or! a group selected from the group consisting of optionally substituted and / or bridged C3-C12 cycloalkyl, C3-C12 cycloalkenyl, C7-C12 polycycloalkyl, C7-C12 polycycloalkenyl, C5-C12 spirocycloalkyl, C3-C12 heterocycloalkyl contains 1-2 heteroatoms, and C3-C12-heterocycloalkenyl, which contains 1-2 heteroatoms, or! R1 and R3 or R2 and R3 together represent a saturated or unsaturated C3-C4 alkyl bridge which may contain 1 heteroatom,! R4 is a group selected from the group consisting of hydrogen, —CN, hydroxy, —NR6R7 and halogen, or! a group selected from the group consisting of optionally substituted C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C5 alkyloxy group, C2-C5 alkenyloxy group, C2-C5 alkynyloxy group, C1-C6 alkylthio group , C1-C6-alkylsulfoxyl group and C1-C6-alkylsulfonyl,! L is a connecting moiety selected from the group consisting of optionally substituted C2-C10-alkyl, C2-C10-alkenyl, C6-C14-aryl, -C2-C4-alkyl-C6-C14-aryl, -C6-C14-aryl- C1-C4 alkyl, optionally bridging C3-C12 cycloalkyl and heteroaryl, which contains 1 or 2 nitrogen atoms,! n is 0 or 1,! m is 1 or 2,! R5 is a group selected from the group consisting of optionally substituted morpholinyl, n |
priorityDate | 2004-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 797.