http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010136301-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46 |
| filingDate | 2009-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010136301-A |
| titleOfInvention | TRIAZOLE DERIVATIVE AND ITS APPLICATION AS VAP-1 INHIBITOR |
| abstract | 1. The compound represented by formula (I):! R 1 -NH-X-Y-Z (I)! where! R1 represents acyl; ! X represents a divalent residue derived from optionally substituted thiazole; ! Y has the formula (III):! J-L-M (III)! where J is a bond, lower alkylene, lower alkenylene, lower alkynylene, - (CH2) nO-, - (CH2) n-NH-, - (CH2) n-CO- or - (CH2) n-SO2- (where n is an integer from 0 to 6); ! L is a bond, —O—, —NH—, —CO—, or —SO2—; ! M is a bond, lower alkylene, lower alkenylene or lower alkynylene, provided that when J is - (CH2) nO-, L is not -O-, -NH- and -SO2- when J is - ( CH2) n-NH-, L is not -O- and -NH- when J is - (CH2) n-CO-, L is not -CO- when J is - (CH2) n-SO2- , L is not -O- and -SO2- (where n is as defined above),! Z has the formula (II):! A-B-D-E (II)! where A represents a divalent residue derived from optionally substituted benzene, or a divalent residue derived from optionally substituted thiophene; ! B is - (CH2) l-NR2-CO-, where R2 is hydrogen, lower alkyl or acyl, l is an integer from 1 to 6, - (CH2) mO-CO- or - (CH2) mS-CO - (where m is an integer from 0 to 6); ! D is —NR3— where R3 is hydrogen, lower alkyl, alkoxycarbonyl or acyl; and! E is an optionally substituted amino; ! or a pharmaceutically acceptable salt thereof. ! 2. The compound according to claim 1, where the compound represented by the above formula (I) is! 4- {2- [2- (acetylamino) -1,3-thiazol-4-yl] ethyl} phenylhydrazinecarboxylate,! 4- {2- [2- (acetylamino) -1,3-thiazol-4-yl] ethyl} benzylhydrazinecarboxylate,! 2- (4- {2- [2- (acetylamino) -1,3-thiazol-4-yl] ethyl} phenyl) ethylhydrazinecarboxylate,! |
| priorityDate | 2008-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.