http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010135499-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-35 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-695 |
filingDate | 2010-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2010135499-A |
titleOfInvention | ANALOGUES OF ADRENCORTICOTROPIC HORMONE AND RELATED METHODS |
abstract | 1. A composition comprising an isolated adrenocorticotropic hormone peptide analog (ACTH) or a pharmaceutically acceptable salt thereof, wherein the peptide analog is a compound of the following formula:! A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-Asn- A26-Ala-Glu-A29-A30-Ser-Ala-Glu-Ala-Phe-A36-Leu-Glu-Phe-R,! wherein: ! A1 represents Ser or D-Ser; ! A2 represents Tyr or D-Tyr; ! A3 is Ser or D-Ser; ! A4 is Met, D-Met or Nle; ! A5 represents Glu, D-Glu, Cys or Asp; ! A6 is His or D-His; ! A7 is Phe, D-Phe, D-p-iodo-Phe or D-1-naphtha-Ala; ! A8 is Arg or D-Arg; ! A9 represents Trp or D-Trp; ! A10 represents Gly, Cys, Lys, Orn, Dab or Dpr; ! A11 is Lys, D-Lys or Gly; ! A12 is Pro or D-Pro; ! A13 represents Val or D-Val; ! A14 is Gly or D-Gly; ! A15 represents Lys, Arg, Ala, Gly, Val, Leu, Ile, Gln, Asn, Glu, Asp, Nle or an amino acid with an alkyl side chain; ! A16 represents Lys, Arg, Ala, Gly, Val, Leu, Ile, Gln, Asn, Glu, Asp, Nle or an amino acid with an alkyl side chain; ! A17 represents Lys, Arg, Ala, Gly, Val, Leu, Ile, Gln, Asn, Glu, Asp, Nle or an amino acid with an alkyl side chain; ! A18 is Lys, Arg, Ala, Gly, Val, Leu, Ile, Gln, Asn, Glu, Asp, Nle or an amino acid with an alkyl side chain; ! A19 is Pro, Trp, or Ala; ! A20 represents Val or Ala; ! A21 is Lys, Ala Pro or Glu; ! A22 represents Val or Ala; ! A23 is Tyr, Ala, Arg, or deleted; ! A24 is Pro or Ala; ! A26 represents Gly, Val or Phe; ! A29 represents Asp or Asn; ! A30 represents Glu or Lys; and! A36 is Pro or Arg; ! where a) R represents OH or a pharmaceutically acceptable salt group; and! b) Lys and Arg |
priorityDate | 2004-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.