http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010126478-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate | 2008-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010126478-A |
| titleOfInvention | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF OBESITY-ASSOCIATED DISEASES CONTAINING AN INSULINOTROPIC PEPTIDE CONJUGATE |
| abstract | 1. Composition for the treatment of obesity-related diseases, containing a conjugate of an insulinotropic peptide obtained by binding of an insulinotropic peptide to an immunoglobulin Fc region through a non-peptidyl linker selected from the group consisting of SMCC (succinimidyl-4- (N-maleimido-methyl) cyclohexane-1 -carboxylate), SFB (succinimidyl-4-formylbenzoate), polyethylene glycol, polypropylene glycol, polyvinylpyrrolidone, copolymers of ethylene glycol and propylene glycol, polyoxyethylated polyols, polyvinyl alcohol, polysaccharide s, dextran, polyvinyl ethyl ether, biodegradable polymers such as PLA (polylactic acid) and PLGA (polylactic-glycolic acid), lipid polymers, chitins, hyaluronic acid, and combinations thereof. ! 2. The composition for treating obesity-related diseases according to claim 1, wherein the insulinotropic peptide is selected from the group consisting of GLP-1, exendin-3, exendin-4 or their agonists, derivatives, fragments, variants and combinations. ! 3. The composition for treating obesity-related diseases according to claim 2, in which the derivatives are obtained using any method selected from replacement, deletion and modification of the N-terminal amino group of the native insulinotropic peptide, and selected from the group consisting of insulinotropic peptides, fragments thereof and options. ! 4. The composition for treating obesity-related diseases according to claim 3, in which the derivatives are derivatives of exendin-4, and are selected from the group consisting of its derivative with a deleted N-terminal amino group, its derivative obtained by replacing the N-terminal amino group with a hydroxyl group , its derivative, obtained by the mod� |
| priorityDate | 2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.