http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010123168-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010123168-A |
| titleOfInvention | NUCLEIC ACID COMPLEX AND COMPOSITION FOR DELIVERY OF NUCLEIC ACID |
| abstract | 1. A nucleic acid complex comprising nucleic acid and a highly branched cyclic dextrin. ! 2. The nucleic acid complex according to claim 1, where the amount of highly branched cyclic dextrin is from 1 to 4000 mass parts per mass part of nucleic acid. ! 3. The nucleic acid complex according to claim 1 or 2, wherein the nucleic acid is siRNA. ! 4. The nucleic acid complex according to claim 1 or 2, where the highly branched cyclic dextrin is a glucan with a degree of polymerization of 50-5000, including an internal branched cyclic structural fragment formed by α-1,4-glucosidic bonds and at least one α-1 , 6-glucosidic bond, and an external branched structural fragment associated with an internal branched cyclic structural fragment. ! 5. The nucleic acid complex according to claim 1 or 2, which is an aggregate obtained by mixing a nucleic acid with a highly branched cyclic dextrin in an aqueous solution. ! 6. A composition for delivering a nucleic acid, comprising a nucleic acid complex according to any one of claims 1 to 5, and a carrier for delivering a nucleic acid. ! 7. The nucleic acid delivery composition according to claim 6, wherein the nucleic acid delivery vehicle is a composition comprising (A) diacylphosphatidylcholine, (B) at least one compound selected from cholesterol and its derivatives, and (C) a primary aliphatic amine . ! 8. The nucleic acid delivery composition according to claim 1, wherein component (A) of the nucleic acid delivery vehicle is diacylphosphatidylcholine, wherein the acyl moiety includes |
| priorityDate | 2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.