http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010122337-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
| filingDate | 2008-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010122337-A |
| titleOfInvention | DERIVATIVES 1, 2, 4-TRIAZIN-3, 5-DIONE FOR TREATMENT OF DISORDERS RESPONDING TO MODULATION OF DOPAMINE D3 RECEPTOR |
| abstract | 1. Derivatives of 1,2,4-triazine-3,5-dione of the formula I! ! A is a saturated or unsaturated hydrocarbon chain with a chain length of 4 to 6 carbon atoms, wherein the hydrocarbon chain is not substituted or is substituted by 1, 2 or 3 methyl groups; ! R1 is selected from the group consisting of hydrogen, C1-C3 alkyl, and fluorinated C1-C3 alkyl; ! R2 represents hydrogen, a cyano group, a C1-C3 alkyl group, a C1-C3 alkoxy group, a fluorinated C1-C3 alkyl group or a fluorinated C1-C3 alkoxy group; ! R3 is selected from the group consisting of branched C4-C6 alkyl and C3-C6 cycloalkyl, and! R4 is C1-C6 alkyl, C3-C6 cycloalkyl, fluorinated C1-C3 alkyl and fluorinated C3-C6 cycloalkyl,! physiologically acceptable salts of these compounds, their tautomers and N-oxides. ! 2. The compound according to claim 1, in which R1 represents hydrogen. ! 3. The compound according to claim 1 or 2, in which R2 is selected from the group consisting of hydrogen, methyl, ethyl, fluorinated C1-alkyl, fluorine or chlorine. ! 4. The compound according to claim 1 or 2, in which R2 represents hydrogen. ! 5. The compound according to claim 1 or 2, in which R2 represents methyl. ! 6. The compound according to claim 1 or 2, in which A is selected from the group consisting of (CH2) 4, CH2-CH2-CH (CH3) -CH2, CH2-CH (CH3) -CH2-CH2, cis-CH2- CH = CH-CH2, trans-CH2-CH = CH-CH2, cis-CH2-CH = C (CH3) -CH2, trans-CH2-CH = C (CH3) -CH2, cis-CH2-C (CH3) = CH-CH2 and trans-CH2-C (CH3) = CH-CH2. ! 7. The compound according to claim 6, in which a represents (CH2) 4. ! 8. The compound according to claim 1 or 2, in which R3 is a branched C4-C6 alkyl. ! 9. The compound of claim 6, wherein R3 is tert-butyl. ! 10. The compound according to claim 1 or 2, in which R4 represents fluorinated C1-C2-alkyl, n-propyl, n-butyl, tert-butyl or cyclobutyl. ! 11. The compound of claim 10, in which |
| priorityDate | 2007-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.