http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010120677-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-303 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate | 2008-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010120677-A |
| titleOfInvention | CELL FOR OBTAINING HETEROPROTEINS AND METHOD OF OBTAINING ON ITS BASIS |
| abstract | 1. A method of producing a polypeptide, comprising culturing a cell that stably expresses a bicarbonate transporter and has a transferred DNA encoding the desired polypeptide, which allows the cell to produce the specified polypeptide. ! 2. The method according to claim 1, wherein the cell that stably expresses the bicarbonate carrier is a cell into which DNA encoding the bicarbonate carrier has been transferred. ! 3. The production method according to claim 1 or 2, in which a cell that stably expresses a bicarbonate transporter further stably expresses a cysteinesulfinic acid decarboxylase or alanine aminotransferase. ! 4. The production method according to claim 1 or 2, wherein the bicarbonate carrier is an SLC4 anion exchanger or an SLC26 anion exchanger. ! 5. The production method according to claim 1 or 2, in which the bicarbonate carrier is an SLC4 anion exchanger. ! 6. The production method according to claim 5, in which the SLC4 anion exchanger is AE1. ! 7. The production method according to claim 1 or 2, wherein the cell is a Chinese hamster ovary cell. ! 8. The production method according to claim 1 or 2, in which the desired polypeptide is an antibody. ! 9. The method according to claim 4, in which the DNA encoding the SLC4 anion exchanger is any of the DNAs listed in paragraphs (a) to (e) below:! (a) DNA encoding a polypeptide having the amino acid sequence shown in SEQ ID NO: 2; ! (b) DNA encoding a polypeptide that has an amino acid sequence derived from the amino acid sequence shown in SEQ ID NO: 2 by substitution, deletion, addition and / or insertion of one or more amino acid residues with |
| priorityDate | 2007-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.