http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010106202-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-284 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 |
| filingDate | 2007-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010106202-A |
| titleOfInvention | COMPOSITIONS OF NON-OPIOID AND LIMITED OPIOID ANALGETICS |
| abstract | 1. A pharmaceutical composition having a central and off-center layer, comprising:! (a) hydrocodone, a pharmaceutically acceptable salt or hydrate thereof, and! (b) acetaminophen or ibuprofen, where at least 75% of the hydrocodone, its pharmaceutically acceptable salt or hydrate is in the central part, where acetaminophen or ibuprofen is in the off-center layer and where the composition is adapted so that it is suitable for oral administration to humans 3, 2 or 1 times a day. ! 2. The composition according to claim 1, where more than 90% of hydrocodone, its pharmaceutically acceptable salt or hydrate is located in the Central part. ! 3. The composition according to claim 1, where essentially all of the hydrocodone, its pharmaceutically acceptable salt or hydrate is located in the central part. ! 4. The composition according to claim 1, where, in addition, the Central part further comprises acetaminophen. ! 5. The composition according to claim 1, where, in addition, the Central part further comprises acetaminophen or ibuprofen. ! 6. The composition according to any one of claims 1 or 5, where the central layer contains an excipient capable of controlling the release of the drug, and the off-center layer contains an excipient capable of immediately releasing the drug. ! 7. The composition according to any one of claims 1 to 5, where the central layer is made by extrusion from a melt, followed by direct shaping of the drug-containing melt, and the off-center layer is spray applied to the central layer. ! 8. The composition according to any one of claims 1 to 5, where the composition contains approximately 500 mg of acetaminophen and approximately 15 mg of hydrocodone bitartrate pentahemihydrate. ! 9. A pharmaceutical composition having � |
| priorityDate | 2007-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.