http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010106192-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-02 |
filingDate | 2008-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2010106192-A |
titleOfInvention | ANTIBIOTIC PEPTIDES |
abstract | 1. A peptide or derivative of a peptide with at least 16 amino acid residues and the general formula! Sub1-X1NX2X3PVYIPX4X5RPPHP-Sub2, where! X1 is a neutral residue or molecule with a net positive charge or a positively charged side chain under physiological conditions; ! X2 represents a residue with a polar side chain or a molecule with a total positive charge or a positively charged side chain under physiological conditions; ! X3 is a molecule with a total positive charge or a positively charged side chain under physiological conditions; ! X4 is a neutral residue with a polar side chain, preferably not glutamine, or a molecule with a total positive charge or a positively charged side chain under physiological conditions; ! X5 is a proline or derivative of proline; ! Sub1 is the free N-terminal amino group of amino acid X1 or a modification of the N-terminal amino group; ! Sub2 is a free C-terminal carboxyl group of a C-terminal amino acid or a modification of a C-terminal carboxyl group; ! except for the natural sequences SEQ ID No. 1 (GNNRPVYIPQPRPPHPRI-OH) and SEQ ID No. 2 (GNNRPVYIPQPRPPHPRL-OH). ! 2. The peptide or derivative of the peptide according to claim 1, comprising at least one additional residue X6 and / or X7 in Sub2, where X6 is selected from a proline or derivative of proline or a molecule having, under physiological conditions, a total positive charge or a positively charged side chain, and X7 selected from proline or derivatives of proline, polar molecule or hydrophobic molecule. ! 3. The peptide or derivative of the peptide according to claim 1 or 2, where the remainder of X1 is selected |
priorityDate | 2007-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 209.