http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2010105971-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90209 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2008-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2010105971-A |
| titleOfInvention | METHOD FOR DETERMINING Pyruvate Dehydrogenase (PDH) ACTIVITY AND VISUALIZATION ENVIRONMENT FOR APPLICATION IN THE SPECIFIED METHOD |
| abstract | 1. Method for determining the activity of pyruvate dehydrogenase (PDH) by 13C-MR detection (magnetic resonance detection based on the isotope 13C) using an imaging medium containing hyperpolarized 13C-pyruvate, which detects a 13C-bicarbonate signal and possibly a 13C-pyruvate signal. ! 2. The method of claim 1, wherein the 13C-bicarbonate and 13C-pyruvate signals are detected. ! 3. The method according to claim 1 or 2, which is a method for determining PDH activity in vivo in a human or non-human animal. ! 4. The method according to claim 1 or 2, which is a method for determining PDH activity in vitro in cell culture, in body samples, in ex vivo tissue, or in an isolated organ of human or non-human origin. ! 5. The method of claim 1, wherein said signal or signals are used to generate a metabolic profile. ! 6. The method according to claim 5, which is carried out in vivo or in vitro, and wherein the information obtained is used in evaluating the efficacy of potential drugs that alter the activity of PDH. ! 7. The method according to claim 5, which is carried out in vivo or in vitro, and where the obtained information is used to assess the response to treatment and / or to determine the effectiveness of treatment in sick patients being treated for their disease. ! 8. The method according to claim 5, which is carried out in vivo or in vitro, and where the obtained information is used to identify patients at risk of developing the disease and / or candidates for preventive measures to avoid the development of the disease. ! 9. The method according to claim 5, which is carried out in vivo or in vitro, and where the obtained information is used for early detection of diseases. ! 10. Method according to � |
| priorityDate | 2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID407698408 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID160434 |
Total number of triples: 15.