http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009148507-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-26 |
filingDate | 2008-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2009148507-A |
titleOfInvention | Derivative of tetrahydroisoquinoline-1-one or its salt |
abstract | 1. The tetrahydroisoquinolin-1-one derivative represented by the general formula (I), or a pharmaceutically acceptable salt thereof:! ! the symbols in the formula have the following meanings:! R1: lower alkylene-OH, lower alkylene-N (R0) (R6), lower alkylene-CO2K0, cycloalkyl, cycloalkenyl, aryl, heterocyclic group, - (lower alkylene, substituted -OR0) -aryl or lower alkylene-heterocyclic group, ! where lower alkylene, cycloalkyl, cycloalkenyl, aryl and a heterocyclic group in R1 may each be substituted,! R0: identical or different from each other, each means -H or lower alkyl,! R6: R0, -C (O) -R0, -CO2-lower alkyl or -S (O) 2-lower alkyl,! R2: lower alkyl, lower alkylene-OR0, lower alkylene-aryl, lower alkylene-heterocyclic group, lower alkylene-N (R0) CO-aryl, lower alkylene-O-lower alkylene-aryl, -CO2R0, -C (O) N (R0) 2, -C (O) N (R0) -aryl, -C (O) N (R0) -lower alkylene-aryl, aryl or heterocyclic group,! where the aryl and heterocyclic group in R2 may each be substituted,! R3: -H or lower alkyl,! or R2 and R3 may be combined to form C2-6 alkylene; ! R4: -N (R7) (R8), -N (R0) -OH, -N (R10) -OR7, -N (R0) -N (R0) (R7), -N (R0) -S (O ) 2-aryl or N (R0) -S (O) 2-R7,! where the aryl in R4 may be substituted,! R7: lower alkyl, halogen-lower alkyl, lower alkylene-CN, lower alkylene-OR0, lower alkylene-CO2R0, lower alkylene-C (O) N (R0) 2, lower alkylene-C (O) N (R0) N (R0) 2, lower alkylene-C (= NH) NH2, lower alkylene-C (= NOH) NH2, heteroaryl, lower alkylene-X-aryl or lower alkylene-X-heterocyclic group,! where lower alkylene, aryl, heteroaryl and a heterocyclic group in R7 may each be substituted,! X: single bond, —O—, —C (O) -, —N (R0) -, —S (O) p- or * -C (O) N (R0) -,! where * in X matters from bond to lower alkylene,! m: integer from 0 to 3,! p: integer from 0 to 2,! R8: -H or lower � |
priorityDate | 2007-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 81.