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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-04
filingDate 2008-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2009147451-A
titleOfInvention 1-SUBSTITUTED TETRAHYDROISOCHINOLINE DERIVATIVE
abstract 1. The compound of formula (I) !! where R1a and R1b are the same or different and are —H, C1-6 alkyl which may be substituted, cycloalkyl which may be substituted, aryl which may be substituted, or an aromatic heterocycle which may be substituted, provided that both of R1a and R1b cannot be —H, and R1a and R1b, taken together with the carbon atom to which they are attached, can be cycloalkyl, which can be substituted,! R3a, R3b, R4a and R4b are the same or different and are —H or C1-6 alkyl,! R5, R6, R7 and R8 are the same or different and are —H, C1-6 alkyl which may be substituted, —O- (C1-6 alkyl) which may be substituted, cyano, carbamoyl which may be substituted with one or two C1-6alkyl, or halogen, and any two adjacent groups R5, R6, R7 and R8 taken together can form —O — CH 2 —O— or —O— (CH 2) 2 — O—,! R11, R12, R13, R14, R15 and R16 are the same or different and are —H or C1-6 alkyl,! R21 is —H, C1-6 alkyl which may be substituted, or cycloalkyl which may be substituted! R22 represents! (1) cycloalkyl, which is substituted by one or more groups selected from the group consisting of —OH and —CH2OH, and which may be further substituted; ! (2) C1-8 alkyl substituted with one or two -OH, where C1-8 alkyl may have an additional substituent, and one or two methylene groups (-CH2-) contained in this alkyl chain may be replaced with -O-; or ! (3) C1-6alkyl substituted with cycloalkyl, which is substituted with one or more groups selected from the group consisting of -OH and -CH2OH, and which may be further substituted, where C1-6alkyl may be substituted with -OH, and one or two mark
priorityDate 2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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