http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009147297-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 |
| filingDate | 2008-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009147297-A |
| titleOfInvention | TRIAZOLE COMPOUNDS FOR TREATMENT OF FORMATION OF BIOFILMS |
| abstract | 1. The use of the compounds of formula I! ! where R1 and R5 simultaneously or independently from each other denote hydrogen, halogen, hydroxyl, (ness.) alkyl, halogen (ness.) alkyl, (ness.) alkoxy group, halogen (ness.) alkoxy group, carboxyl, carbamoyl, N- ( ness.) alkylcarbamoyl, N, N-di (ness.) alkylcarbamoyl or nitrile,! R2 and R4 simultaneously or independently from each other denote hydrogen, unsubstituted or substituted (ness.) Alkanoyl or aroyl, or a radical that can be removed under physiological conditions,! R3 is hydrogen, lower alkyl, hydroxy lower alkyl, halogen lower alkyl, carboxy lower alkyl, lower alkoxy carbonyl lower alkyl, R6 R7-C (O) - ( ness.) alkyl, unsubstituted or substituted aryl or aryl (ness.) alkyl, or unsubstituted or substituted heteroaryl or heteroaralkyl! R6 and R7, simultaneously or independently from each other, denote hydrogen, (ness.) Alkyl, hydroxy (ness.) Alkyl, alkoxy (ness.) Alkyl, hydroxyalkoxy (ness.) Alkyl, amino (ness.) Alkyl, N- (ness. .) alkylamino (lower) alkyl, N, N-di (lower) alkylamino (lower) alkyl, N- (hydroxy (lower) alkyl) amino (lower) alkyl, N, N-di (hydroxy ( ness.) alkyl) amino (ness.) alkyl, or together with the nitrogen atom to which they are attached form an azaalicyclic ring! and where the prefix (ness.) denotes a radical containing not more than 7 carbon atoms,! for the manufacture of a medicament for treating the formation of P. aeruginosa biofilms in a patient with cystic fibrosis. ! 2. The use according to claim 1, where the compound of formula I is 4- [3,5-bis (2-hydroxyphenyl) - [1,2,4] triazol-1-yl] benzoic acid or a pharmaceutically acceptable salt thereof. ! 3. A combination comprising (a) 4- [3,5-bis (2-hydroxyphenyl) - [1,2,4] triazol-1-yl] benzoic acid or its pharmacist |
| priorityDate | 2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.