http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009143362-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D255-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-417 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-89 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 |
| filingDate | 2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009143362-A |
| titleOfInvention | DUAL ACTION ANTIHYPERTENSIVE |
| abstract | 1. The compound of formula I:! ! where r represents 0, 1 or 2; ! Ar is selected from! and! R1 is selected from -COORla, -NHSO2R1b, -SO2NHR1d, -SO2OH, -C (O) NH-SO2R1c, -P (O) (OH) 2, -CN, -O-CH (R1e) -COOH, tetrazole -5-silt! and! R1a is H, -C1-6alkyl, -C1-3alkylenearyl, -C1-3alkyleneheteroaryl, -C3-7cycloalkyl, -CH (C1-4alkyl) OC (O) R1aa, -C0-6alkylene-morpholine,! or ! R1aa is —O — C1-6alkyl, —O — C3-7cycloalkyl, —NR1abR1ac or —CH (NH2) CH2COOCH3; R1ab and R1ac are independently selected from H, -C1-6 alkyl and benzyl, or taken together as - (CH2) 3-6-; R1b represents R1c or —NHC (O) R1c; R1c is —C1-6alkyl, —C0-6alkylene-O-R1ca, —C1-5alkylene-NR1cbR1cc, —C0-4alkylenearyl or —C0-4alkyleneheteroaryl; R1ca is H, C1-6alkyl, or C1-6alkylene-O-C1-6alkyl; R1cb and R1cc are independently selected from H and -C1-6 alkyl or taken together as - (CH2) 2-O- (CH2) 2- or - (CH2) 2-N [C (O) CH3] - (CH2) 2- ; R1d is H, R1c, —C (O) R1c or —C (O) NHR1c; R1e is —C1-4alkyl or aryl; ! Y is —C (R3) -, Z is —N—, Q is —C (R2) -, and W is a bond; Y is —N—, Z is —C (R3) -, Q is —C (R2) -, and W is a bond; Y represents —C (R3) -, Z represents —N—, Q represents —N—, and W represents a bond; Y is —C (R3) -, Z is —CH—, Q is —N—, and W is a bond; or Y is —C (R3) -, Z is —CH—, Q is —C (R2) -, and W is —C (O) -; ! R2 is selected from H, halogen, —NO2, —C1-6 alkyl, —C2-6 alkenyl, —C3-6 cycloalkyl, —CN, —C (O) R2a, —C0-5 alkylene-OR2b, —C0-5 alkylene-NR2cR2d, - C0-3 alkylene aryl and -C0-3 alkylene heteroaryl; where R2a is selected from H, -C1-6alkyl, -C3-6cycloalkyl, -OR2b and -NR2cR2d; R2b is selected from H, -C1-6 alkyl, -C3-6 cycloalkyl and -C0-1 alkylenearyl; and R2c and R2d are independently selected from H, -C1-4 alkyl and -C0-1 alkyl |
| priorityDate | 2007-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.