http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009143324-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 2008-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009143324-A |
| titleOfInvention | OPHTHALMIC OIL-IN-WATER EMULSIONS CONTAINING PROSTAGLANDINS |
| abstract | 1. An oil-in-water emulsion for ophthalmic use, having mainly a neutral zeta potential and containing as components! (i) the dispersed oil phase,! (ii) at least one prostaglandin as an active agent that is soluble in the oil phase component (i),! (iii) a surfactant component comprising a combination of at least two non-ionic surfactants, and! (iv) an adjacent aqueous phase, optionally containing composition agents. ! 2. The oil-in-water emulsion according to claim 1, wherein the oil phase (i) is present in an amount of at least 5% (w / w), based on the total weight of the emulsion. ! 3. The oil-in-water emulsion according to claim 1, wherein the oil phase component (i) is selected from pharmaceutically acceptable oils, such as animal or vegetable oils, synthetic oils, and mixtures thereof. ! 4. The oil-in-water emulsion according to claim 1, wherein the oil phase component (i) is selected from the group consisting of ethyl oleate, a mixture of triglycerides of C8-C10 fatty acids, castor oil, corn oil, or mixtures thereof. ! 5. The oil-in-water emulsion according to claim 1, wherein the oil phase (i) has a solubilization degree of at least 0.1 mg / ml with respect to the prostaglandin component (ii). ! 6. The oil-in-water emulsion of claim 5, wherein the oil phase (i) has a solubilization degree of at least 10 mg / ml with respect to the prostaglandin component (ii). ! 7. The oil-in-water emulsion according to claim 1, wherein the partition coefficient of the prostaglandin component (ii) between the oil / water is at least log P = 0.5 in favor of the oil phase (i). ! 8. The oil-in-water emulsion according to claim 7, in which the distribution coefficient of the prostaglandin component (ii) |
| priorityDate | 2007-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.