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filingDate 2008-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2009142806-A
titleOfInvention NANOPARTICLES INCLUDING CYCLODEXTRINS AND A BIOLOGICALLY ACTIVE MOLECULE, AND THEIR APPLICATION
abstract 1. Nanoparticles comprising a biodegradable polymer, cyclodextrin or its derivative and biologically active molecule. ! 2. The nanoparticles according to claim 1, where the specified biodegradable polymer is a copolymer of methyl vinyl ether and maleic anhydride (PVM / MA). ! 3. The nanoparticles according to claim 1, where the specified cyclodextrin or its derivative is selected from the group consisting of β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin, 6-monodeoxy-6-monoamine-β-cyclodextrin and mixtures thereof. ! 4. Nanoparticles according to claim 1, comprising two or more biologically active molecules. ! 5. The nanoparticles according to claim 1, where the specified biologically active molecule is a small chemical molecule, protein, peptide, nucleoside, nucleotide, oligonucleotide, polynucleotide or nucleic acid. ! 6. The nanoparticles according to claim 1, where the specified biologically active molecule is a drug, antigen or allergen. ! 7. The nanoparticles according to claim 1, where the specified biologically active molecule is a hydrophobic substance or a substrate substance of the enzyme P-glycoprotein. ! 8. The nanoparticles according to claim 1, where the specified biologically active molecule is selected from the group consisting of actinomycin D, albendazole, amitriptyline, amprenavir, atorvastatin, bunitrolol, camptothecin, carvedilol, celiprolol, cyclosporine, clotrimazole, colchicine, cortisone, debrisouin, dauborizin, da dexamethasone, digitoxin, digoxin, diltiazem, docetaxel, domperidone, doxorubicin, epirubicin, erythromycin, estradiol, etoposide, phenytoin, fexofenadine, FK506, fluorouracil, gentamicin, griseofinvin, imine, imine, rakonazola, levofloxacin, losartan,
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