http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009140731-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-25 |
| filingDate | 2008-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009140731-A |
| titleOfInvention | PHARMACEUTICAL COMPOSITIONS CONTAINING GHRH MOLECULES |
| abstract | 1. A liquid pharmaceutical composition containing a GHRH molecule, an anionic surfactant and non-reducing sugar,! where the composition has a pH of from about 4.0 to about 7.5, where the GHRH molecule is an analogue of the GHRH of formula A! X-GHRH peptide, (A)! where the GHRH peptide is a peptide of formula B! A1-A2-Asp-Ala-Ile-Phe-Thr-A8-Ser-Tyr-Arg-Lys-A13-Leu-A15-Gln-Leu-A18-Ala-Arg-Lys-Leu-Leu-A24-A25- Ile-A27-A28-Arg-A30-R0, (B) (SEQ ID NO: 1)! where A1 represents Tyr or His; ! A2 represents Val or Ala; ! A8 represents Asn or Ser; ! A13 represents Val or Ile; ! A15 is Ala or Gly; ! A18 is Ser or Tyr; ! A24 represents Gln or His; ! A25 represents Asp or Glu; ! A27 is Met, Ile or Nle; ! A28 represents Ser or Asn; ! A30 is a bond or amino acid sequence containing from 1 to 15 residues; and! R0 represents NH2 or NH- (CH2) n-CONH2, where n = 1 to 12; and! X represents a hydrophobic tail attached via an amide bond to the N-terminus of the peptide, said hydrophobic tail having from 5 to 7 carbon atoms in the main chain; ! wherein the main chain may contain substituents, such as C1-6 alkyl, C3-6 cycloalkyl or C6-12 aryl, and the main chain includes at least one stiffening moiety associated with at least two atoms of the main chain; ! wherein said portion is a double bond, a triple bond, saturated or unsaturated C3-9 cycloalkyl or C6-12 aryl. ! 2. The composition according to claim 1, where X represents! ! 1 (R = H or CH3 or CH2CH3)! cis or trance! ! 2 (R = H or CH3 or CH2CH3)! ! 3 (R = H or CH3 or CH2CH3)! cis or trance, as in the form! racemic mixtures like that! in the form of pairs of pure enantiomers! ! 4 (R = H or CH3 or |
| priorityDate | 2007-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.