http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009139004-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-197 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4436 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427 |
| filingDate | 2008-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009139004-A |
| titleOfInvention | COMBINED MEDICINES FOR THE TREATMENT OF BACTERIAL INFECTIONS |
| abstract | 1. The use of a monobactam antibiotic of the formula (I)! ! in which the oxyimino group, i.e.> C = N — O—, has a Z orientation, or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for treating a bacterial infection in combination with one or more carbapenem antibiotics or their pharmaceutically acceptable salts. ! 2. The use according to claim 1, where the drug is intended for the treatment of infections caused by gram-positive and / or gram-negative bacteria, in particular gram-negative bacteria. ! 3. The use according to claim 1 or 2 for the treatment of bacterial infections in combination with one carbapenem antibiotic or its pharmaceutically acceptable salt. ! 4. The use according to claim 3, where the carbapenem antibiotic is a compound of formula (II)! ! where R1 represents hydrogen or C1-C6 alkyl; ! R2 is hydrogen or C1-C6 alkyl; ! R3 is hydrogen, C1-C6 alkyl, C1-C6 alkoxy; - (C1nH2n) -R5 or -O- (C1nH2n) -R5; ! where R5 is halogen, cyano, C1-C6 alkoxy, amino; (C1-C6 alkyl) amino, di (C1-C6 alkyl) amino or a group of the formula -CO-R6, -NH-CO-R6 -CO-NH2, -NH-CO-NH2, -NH-SO2-NH2 or -NH- (C = NH) -NH2, in these groups one or more hydrogen atoms can also be replaced by R6 or -NH2, the remainder of the group can be replaced by a 5-6 membered heterocyclic ring bonded to the group via a nitrogen atom present in the ring, where the heterocyclic ring may be unsubstituted or substituted by one or more substituents S2, where each S2 has, independently of the other substituents S2, one of the meanings given below; and! R6 represents a C1-C6 alkyl, phenyl or 5-6 membered heterocyclic ring and may |
| priorityDate | 2007-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID163770524 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465456940 |
Total number of triples: 26.