http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009136591-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-66 |
| filingDate | 2009-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009136591-A |
| titleOfInvention | Derivatives of five-membered heterocycles, a method for their production and their use as drugs |
| abstract | 1. The use of the compounds of general formula (I) 1:! ! in which X is S; ! A stands for the radical:! ! in which Q is OH, two of the radicals R19, R20 and R21 are alkyl, and the third is H,! B is H,! n means 0 or 1! R1 and R2 are both H and! Ω means:! or the radical NR46R47, where one of R46 and R47 is H or hydroxyalkyl, alkynyl or cyanoalkyl and the other is H or alkyl; ! either OH radical; ! or salts of such a compound! to obtain a medicinal product intended for the treatment of the following pathologies: disorders of the central or peripheral nervous system, schizophrenia, depression, psychosis, memory and mood disorders, behavior disorders, bulimia and anorexia, autoimmune and viral diseases, dependence on toxic substances. ! 2. The use according to claim 1 of a compound selected from the following compounds:! 4- [3,5-bis (1,1-dimethylethyl) -4-hydroxyphenyl] -N-methyl-2-thiazolemethanamine; ! 2,6-di (tert-butyl) -4- (2 - {[methyl (2-propynyl) amino] methyl} -1,3-thiazol-4-yl) phenol; ! 2 - [({4- [3,5-di (tert-butyl) -4-hydroxyphenyl] -1,3-thiazol-2-yl} methyl) (methyl) amino] acetonitrile; ! -5 - [({4- [3,5-di (tert-butyl) -4-hydroxyphenyl] -1,3-thiazol-2-yl} methyl) (methyl) amino] pentannitrile; ! 6 - [({4- [3,5-di (tert-butyl) -4-hydroxyphenyl] -l, 3-thiazol-2-yl} methyl) (methyl) amino] hexannitrile; ! 2,6-di (tert-butyl) -4- (2 - {[((2-hydroxyethyl) (methyl) amino] methyl} -1,3-thiazol-4-yl) phenol; ! 4 - [{[4- (3,5-ditret-butyl-4-hydroxyphenyl) -1,3-thiazol-2-yl] methyl} (methyl) amino] butanitrile; ! 2,6-diisopropyl-4- {2 - [(methylamino) methyl] -1,3-thiazol-4-yl} phenol; ! 2,6-ditret-butyl-4- [2- (hydroxymethyl) -1,3-thiazol-4-yl] phenol! or salts of such a compound. ! 3. The use according to claim 1 or 2 for the manufacture of a medicament for the treatment of |
| priorityDate | 1999-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.