http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009136340-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2009136340-A |
| titleOfInvention | COMPOSITIONS OF RECOMBINANT ANTIBODIES AGAINST EPIDERMAL GROWTH FACTOR RECEPTOR |
| abstract | 1. A recombinant antibody composition comprising at least 3 different anti-EGFR antibody molecules, the antibodies binding different first, second and third EGFR epitopes. ! 2. The recombinant antibody composition of claim 1, wherein the epitopes are non-overlapping. ! 3. The recombinant antibody composition of claim 1, wherein the at least one individual antibody molecule is capable of suppressing EGF binding. ! 4. The recombinant antibody composition according to claim 1, in which at least one individual antibody molecule is capable of preventing EGFR phosphorylation. !5. The recombinant antibody composition of claim 1, wherein the at least one individual antibody molecule is capable of enhancing EGFR internalization / degradation. ! 6. The recombinant antibody composition according to claim 1, containing at least one additional different anti-EGFR antibody molecule, wherein said additional antibody binds a fourth individual epitope. ! 7. The recombinant antibody composition according to claim 6, containing at least one additional different anti-EGFR antibody molecule, wherein said additional antibody binds a fifth individual epitope. ! 8. The recombinant antibody composition according to claim 7, containing at least one additional different anti-EGFR antibody molecule, wherein said additional antibody binds a sixth individual epitope. ! 9. The recombinant antibody composition according to claim 1, containing at least one domain III antibody and at least one domain I / II antibody. ! 10. The recombinant antibody composition according to claim 1, containing at least two antibodies of domain III and, by exchange |
| priorityDate | 2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.