http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009136263-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
filingDate | 2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2009136263-A |
titleOfInvention | Benzimidazole derivatives and methods for their use |
abstract | 1. A method of treating a pathological condition in a patient, comprising administering to the patient an effective amount of one or more compounds of the formula:! ! or a pharmaceutically acceptable salt, solvate, ester or prodrug thereof, in which:! dashed line means optional and additional connection; ! M1 is C (R3); ! X is a bond or (C1-C6) alkylene; ! Y is —C (O) -, —C (S) -, - (CH2) q-, -C (O) NR4-, -C (O) CH2-, -SO2-, or -C (= N- CN) —NH—, so if M1 is N, Y is not —C (O) NR4— or —C (= N — CN) —NH—; ! Z is a bond, (C1-C6) alkylene, C1-C6 alkenylene, -C (O) -, -CH (CN) - or -CH2C (O) NR4-; ! R1 means! ,,,,,! , , or ; ! Q is —N (R8) -, —S— or —O—; ! R is H, OH, (C1-C6) alkyl, halogen (C1-C6) alkyl, (C1-C6) alkoxy, (C1-C6) alkoxy- (C1-C6) alkyl, (C1-C6) alkoxy- (C1-C6) alkoxy group, (C1-C6) alkoxy- (C1-C6) alkyl-SO0-2, R32-aryl (C1-C6) alkoxy group, R32-aryl (C1-C6) alkyl, R32-aryl, R32 -aryloxy group, R32-heteroaryl, (C3-C6) cycloalkyl, (C3-C6) cycloalkyl- (C1-C6) alkyl, (C3-C6) cycloalkyl- (C1-C6) alkoxy group, (C3-C6) cycloalkyloxy group, R37 -heterocycloalkyl, N (R3O) (R3l) - (C1-C6) alkyl, -N (R30) (R31), -NH- (C1-C6) alkyl-O- (C1-C6) alkyl, -NHC ( O) NH (R29); R29-S (O) 0-2-, halogen (C1-C6) alkyl-S (O) 0-2-, N (R3O) (R31) - (C1-C6) alkyl-S (O) 0-2 - or benzoyl; ! R2 is a 6-membered heteroaryl ring containing 1 or 2 heteroatoms independently selected from the group consisting of N and N-O, the remaining ring atoms are carbon atoms; 5-membered heteroaryl ring containing 1, 2 or 3 heteroatoms independently selected from the group consisting of N, O and S, the remaining ring atoms are carbon atoms; R32-quinolyl; R32 is aryl; heterocycloalkyl; ! ; ; or , ! where said 6 membered heteroaryl ring or said 5 membered heteroaryl ring is optionally substituted with |
priorityDate | 2007-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1150.